After I've loaded the save game.
April Ryan is my friend,
Every sorrow she can mend.
When i visit her dark realm,
Does it simply overwhelm.
Yeah, that's what I'm doing too.
I don't know if anyone is still interested but I tried all of the solutions mentioned above and was having no success but I remembered that a way to solve two programs not talking to each other is to run both as Administrator. This solution worked well for me: Run Dreamfall as administrator> load a savegame> Alt-tab to desktop (you can also use the windows button if your keyboard has it)> Run the trainer as administrator> click Dreamfall icon on taskbar to re-enter the game> press the hotkeys for your desired cheat. If all went well the trainer window should show your desired cheats as being on and the effects should be noticed the next time you encounter combat/timed puzzle.
If you don't know how to start a program as administrator here is a short guide for windows 7 users: Go to desktop>move mouse cursors over the desktop shortcut of the program you want use>left click the program> the resulting menu should have a option "Run as Administrator", click that option.
I hope this helps.
Nice tip! I'll give it a try.